Human Genome Project - Reference List SCI Home | SCI Faculty Page | Cover Sheet | Case Notes | Users Notes

Last Revised: June 06, 2000

Author - Linda Hensel-Burke - Summer 1998

References

Internet References: Learn about the Human Genome Project at the following sites

• NIH - Policy and Public Affairs
• HHMI's Blazing a Genetic Trail: Research on Mutant Genes and Hereditary Diseases.
• HHMI's Blazing a Genetic Trail: Research on Mutant Genes and Hereditary Diseases: Reading the Human Blueprint
• DOE Human Genome Program Home Page
• for AP Biology students Human Genome Education Program
• Projects in Ethical, Legal, and Social Issues

Science frequently contains both primary and secondary literature related to the Human Genome Project.

• Koonin (1998, An Independent Perspective on the Human Genome Project. Science 279:36)
  discusses the Human Genome project as "big science" relative to other big science endeavors such as space and planetary science. This article could potentially be a tool for a class discussion on the management of big science.
• Pennisi (1998, Sifting Through and Making Sense of Genome Sequences, Science 280:1692)
  reports from the latest Genome meeting on what scientists are doing to make sense of all of the DNA sequence data they are collecting.
• Venter et al. (1998, Shotgun Sequencing of the Human Genome. Science 280:1540)
  work for private companies--The Institute for Genomic Research and Perkin--Elmer. These authors have devised a method for sequencing the entire human genome in 3 years and have begun to do so. If successful, they will finish well before the academic laboratories funded and coordinated by the Human Genome Project (launched in 1990 and proposed completion in 2005). Are the duplicated efforts necessary? This article would be a good tool for generating a discussion about spending tax dollars for science.

Hard copies available

Folders containing the following reference material are available: Chapter 22 from Trefil and Hazen’s The Sciences--An Integrated Approach outlines the basic genetic information necessary for faculty to teach the material. Articles from both sides of three ethical debates related to the Human Genome Project enclosed as well. A copy of the above Science articles are also available.